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From an athletic point of view, certain types of anabolic steroids are frequently mentioned as having bad effects on liver function, such as oral drugs that are classified as 17-alpha alkylated drugsor anabolic drugs that are classified as 17-beta alkylated drugs. In the case of oral drugs, they can lead to adverse effects of liver toxicity. Therefore, the risk of liver toxicity associated with oral drugs from anabolic steroids is the same as with oral drugs that are classified as 17-alpha alkylated drugs. Oral drugs that are 16-beta alkylated are classified as "undetectable" by the F.D.A. Oral contraceptives have also been associated with a higher occurrence of liver dysfunction, as they contain various 17-alpha alkylated drugs. The most prevalent of these 17-alpha alkylated drugs is norethindrone, which has been reported to increase the incidence of hepatotoxicity. This medication is used to block the receptors for androgens and estrogens through the estrogen receptor. It is very important for the gynecological practitioner to educate patients regarding the risks of anabolic steroids and to provide these patients with appropriate and accurate information regarding their usage. Drugs that are classified as 17-beta alkylated drugs are considered to be atypical and have no clinically significant interaction with other drugs. Therefore, the use of these drugs is not usually discouraged. However, there are situations where they should not be used. In situations in which anabolic steroids are the sole purpose of therapy and are considered to be "non-selective and non-narcotic agents," there are some side effects and risks associated with these therapies. Side effects and risks associated with oral medications must be considered when considering the potential risks for such a medication. A more in-depth discussion of these issues can be found in the article "Steroid Use and Liver Metabolism," available at http://www.gut.org/patient/adrenal-supplements/steroids.aspx . Dosing, Administration and Routines Many physicians prescribe anabolic steroids. When considering an anabolic steroid regimen, a clinician should look at factors such as the patient's history of liver problems or liver enzyme changes, the frequency of steroid injections, and the length of time before the initial steroid injection is needed to ensure that the steroid regimen is providing the desired response. Anabolic steroids can have various dosing schedules, such as the duration and quantity of injections to be given before the liver is adequately prepared and used for its function. Steroid patients who are receiving a high level of steroids and who are on a diuretic or diuretic-induced di Related Article: