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As injectable LGD-4033 is more bioavailable, the dosage required to replicate the anabolic activity I was shooting for would likely be much lower than you would expect via oral dosingalone. Furthermore, in my research, no one I have tested has ever found such a huge reduction in plasma testosterone, even over a week, but I think LGD-4033 may be enough to give it away. (For comparison, the following day, using the same dose and same day cycle, a human who is currently on T and testosterone (or some other anabolic form of steroid) will also exhibit a significant reduction in testosterone.)LGLI believe I have yet to find a case in which a testosterone analog that does not have a high likelihood of causing unwanted side-effects. The most common concerns are that it raises cortisol, can raise the risk for hypertension, and will have a negative impact on liver function, though none of them are likely to be fatal in most cases. Although both LGD-4033 and T with anandamide are similar, they are not the same molecule; LGD-4033 has a higher affinity for the adrenal cortex, thus making LGD-4033 more anandamide sensitive than testosterone.The reason this is important is that using LGD-4033 as a low-dose alternative to T or testosterone supplements in patients who do not respond to low-dose T is not the preferred choice if you truly think their problem is related to low-dose T. If that were the case, one would hope that some of the symptoms described below could be eliminated entirely with a relatively low dose or cycle.LGLTo address the concerns I mentioned above about LGD-4033 or other anandamide analogs, I am now prescribing LGD-4033 to a number of my female patients who can demonstrate an azo-response after only a few days of therapy. I am also consulting with colleagues to better understand the effects of this azo-response and consider it a promising new avenue of study. I will try to update these patients as I go.What is LGD-4033 in humans?If you ever heard of LGL, the brand name name for Luteolin (and also known in some parts of Asia as Anastrozole®), then you may have heard this brand name brand of anandamide marketed by IMS, or perhaps you have heard that in addition to LGL there is also a LGL-4/a-delta hybrid version with the same name. In the US, this type of product was sold as a contraceptive called LEM.Similar articles: